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WELCOME TO SESTI LAB

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The laboratory studies the physiology, regulation, and biophysics of potassium (K+) channels. These multipronged proteins are at the crossroad of multiple cellular functions including excitablity, proliferation and growth, survival, and death. Current projects focus on elucidating the role of K+ channels in neurodevelopment, metabolic disorders, epilepsy Alzheimer's disease, and traumatic brain injury. We are also assessing the potential therapeutic of second-generation Bcr-Abl and Src tyrosine kinase inhibitors and BACE1 inhibitors for the treatment of those pathologies.

SELECTED NEWS


Aniket presented a poster titled “The Role of the IKC–Leptin Receptor Complex in Cortical Neurodevelopment” at the National Collegiate Undergraduate Research Symposium at Harvard University.
In addition, Aniket, Anastasia, Maria del Carmen and Rachel were awarded Aresty Fellowships totaling $1,000 each—congratulations!


A huge toast to Elena! 🥂 She graduated first in her class in Neuroscience—an outstanding achievement we’re all incredibly proud of. Elena successfully defended her thesis, “Tripartite IKC–Leptin Receptor Complexes Connect Physiological Neurodevelopment, Endocrine Signaling, and Its Disruption in Developmental and Epileptic Encephalopathies.”Congratulations, Elena, from the entire lab!!! 🎉


Anastasia was selected to give a flash talk and presented a poster at the 11th symposyum of the Rutgers Brain Health Institute on December 3rd 2025.

Anika and Aniket presented a poster each at the 2025 National Brainbee competition hosted by the Department of Neuroscience and Cell Biology.
Elena, third from left, receiving her plaque at the symposium
The Molecular Biosciences Graduate Student Organization hosted their Annual Symposium and presented the awards.
Elena was awarded a prestigious 2024 Aaron Shatkin Scholarship Award. The award recognizes outstanding current graduate students who have excelled in their research and coursework with $3000. Congratulations Elena!!

Anika presented a poster entitled "KCNB1-Leptin receptor complexes couple electric and endocrine function in the melanocortin neurons of the hypothalamus." at the 10th symposium of the Rutgers Brain Health institute.


Current and former lab members and close friends congratulate Alessandro on his well deserved accomplishments.
Whoa!! Alessandro graduated in Neuroscience defending his thesis entitled: “Investigating the synergy between conductivity and molecular signaling of the Integrin-KCNB1-complex." Alessandro is ready for his new challenge. He has accepted a postdoctoral position in the Torres-Berrio lab at Harvard. Double congratulations Ale!!

Better and better. Arshleen won first prize for best poster at the AXON 5.0 undergraduate conference hosted by the Nu Rho Psi Neuroscience honor society

Srinidi has developed a software using OpenCV (an open sourced computer vision library) for counting cells utilizing watershed segmentation algorithm. This software can be accessed via the 'SOFTWARE' tab of this website.

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